Infección por el Virus de Inmunodeficiencia Humana: modelo de predicción clínica en pacientes con histoplasmosis diseminada progresiva
Resumen
El objetivo general de este estudio es comparar las características clínicas y los exámenes complementarios de pacientes con SIDA que tengan asociado una histoplasmosis diseminada progresiva (HDP) o una tuberculosis (TBC); y además, comparar estos grupos con un grupo de pacientes con SIDA y otras afecciones diferentes a HDP y TBC, con el propósito de definir una escala de predicción clínica para los casos de HDP. Se realizó un estudio clínico, retrospectivo y comparativo en 150 pacientes con la infección por el VIH pertenecientes a la categoría C. Grupo I, 50 pacientes con HDP; grupo II, 50 pacientes con TBC; grupo III, 50 pacientes con enfermedades asociadas diferentes a HDP y TBC. Nosotros concluimos que en los pacientes con SIDA fue posible predecir el diagnóstico de HDP, diferenciándola de TBC y otras patologías, a través de la aplicación de una escala altamente sensible y específica, basada en la presencia de un síndrome febril prolongado, diarrea, máculas hipercrómicas o pápulas, hepatomegalia, esplenomegalia, leucopenia, trombocitopenia, y niveles elevados de SGOT y LDH.
Human Immunodeficiency Virus infection: Clinical prediction model in patients with progressive disseminated histoplasmosis.
Abstract
The general objective of this study is to compare the clinical and laboratory characteristics of progressive disseminated histoplasmosis (PDH) and tuberculosis (TBC) in AIDS patients, as well as to compare them with a group of AIDS patients with other pathologies, with the purpose of defining a clinical prediction scale for PDH cases. A retrospective comparative clinical study was done in 150 patients diagnosed of having HIV infection belonging to C category. Group I, 50 patients with PDH; group II, 50 patients with TBC; group III, 50 patients with different diseases from PDH or TBC. We conclude that in AIDS patients it was possible to predict a PDH diagnosis, differentiating it from TBC and other pathologies, through the application of a highly sensitive and specific scale, based on the presence of a prolonged fever syndrome, diarrhea, hyperchromic macules or papules, hepatomegaly, splenomegaly, leukopenia, thrombocytopenia, high SGOT and LDH levels.
Human Immunodeficiency Virus infection: Clinical prediction model in patients with progressive disseminated histoplasmosis.
Abstract
The general objective of this study is to compare the clinical and laboratory characteristics of progressive disseminated histoplasmosis (PDH) and tuberculosis (TBC) in AIDS patients, as well as to compare them with a group of AIDS patients with other pathologies, with the purpose of defining a clinical prediction scale for PDH cases. A retrospective comparative clinical study was done in 150 patients diagnosed of having HIV infection belonging to C category. Group I, 50 patients with PDH; group II, 50 patients with TBC; group III, 50 patients with different diseases from PDH or TBC. We conclude that in AIDS patients it was possible to predict a PDH diagnosis, differentiating it from TBC and other pathologies, through the application of a highly sensitive and specific scale, based on the presence of a prolonged fever syndrome, diarrhea, hyperchromic macules or papules, hepatomegaly, splenomegaly, leukopenia, thrombocytopenia, high SGOT and LDH levels.
Palabras clave
HIV; histoplasmosis; modelo de predicción clínica; clinical prediction model
Texto completo:
PDFEnlaces refback
- No hay ningún enlace refback.