Síndrome de Dress en una niña con tumor cerebral
Palabras clave:
Síndrome DREES, hipersensibilidad a medicamentos, carbamazepinaResumen
El síndrome DRESS (Reacción a fármacos con eosinofilia y síntomas sistémicos) es una toxidermia sistémica poco frecuente, caracterizada principalmente por rash, fiebre, disfunción hepática y eosinofilia. Se puede presentar luego de la exposición a ciertos fármacos, con una elevada mortalidad entre el 10% y 30 % de los casos. El diagnóstico no es tan sencillo, por la amplia variedad en la presentación clínica y pruebas de laboratorio. Generalmente, las enfermedades de base y comorbilidades afectan el curso natural y empeoran el pronóstico. Se presenta el caso, de una niña que desarrolla síndrome de DRESS durante su hospitalización en cuidado intensivo.
Summary
DRESS Syndrome in a child with brain tumor.
DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is a rare systemic toxidermia, characterized mainly by rash, fever, hepatic dysfunction and eosinophilia. It can occur after exposure to certain drugs, with an elevated mortality between 10% and 30% of cases. Because of the wide variety of clinical presentation and laboratory tests, the diagnosis is not easy. Generally, the underlying diseases and comorbidities affect the natural course and complicate the prognosis. We present the case of a girl who develops DRESS syndrome during her hospitalization in intensive care.
Key words: DRESS syndrome; drug hypersensitivity; carbamazepine.
Referencias
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